4-Defy Gel Cream
$125.00
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Melanie Jane Skincare — 4-Defy Gel Cream
A weightless gel-cream that hydrates without shine and calms visible redness. Built for balance: microbiome-friendly postbiotics, barrier lipids, and a peptide-antioxidant duo to smooth the look of fine lines—fast-absorbing with a clean, non-sticky finish.
Why it works
Normal, combination, and oily/acne-prone skin that needs hydration without heaviness. Also ideal for redness-prone or easily sensitized skin that struggles with rich creams.
How to use
AM or PM after cleansing and serums. Apply a pea-sized amount to face and neck.
AM: finish with a broad-spectrum mineral SPF.
Pro pairing (simple, no moisturizer layering)
Ceramide NP, Phytosphingosine, Lactobacillus Ferment, Palmitoyl Tripeptide-38, Ergothioneine, Sodium Hyaluronate, Squalane, Caprylic/Capric Triglyceride.
Full INCI
Water (Aqua), Glycerin, Caprylic/Capric Triglyceride, Propanediol, Cetearyl Alcohol, Squalane, Cocos Nucifera (Coconut) Fruit Extract, Sodium Stearoyl Glutamate, Carbomer, Sodium Polyacrylate, Diisostearyl Malate, Hexylene Glycol, Sodium Phytate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Hydroxide, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Lactobacillus Ferment, Ceramide NP, Sodium Hyaluronate, Phytosphingosine, Palmitoyl Tripeptide-38, Ergothioneine.
Safety notes
Patch test first. Avoid use on broken/compromised skin. If highly sensitive, start once daily and increase as tolerated. Always use SPF in the morning.
4-Defy Gel Cream
$125.00
A weightless gel-cream that hydrates without shine and calms visible redness. Built for balance: microbiome-friendly postbiotics, barrier lipids, and a peptide-antioxidant duo to smooth the look of fine lines—fast-absorbing with a clean, non-sticky finish.
Why it works
- Ceramide NP + Phytosphingosine: replenishes key barrier lipids for better water retention and resilience.
- Lactobacillus Ferment (postbiotic): helps soothe reactivity and support a balanced skin microbiome.
- Palmitoyl Tripeptide-38: signals smoother-looking texture and firmness over time.
- Ergothioneine: a high-efficiency antioxidant that buffers everyday environmental stress.
- Sodium Hyaluronate: draws in water for lasting, lightweight hydration.
- Squalane + Caprylic/Capric Triglyceride: non-greasy emollients that moisturize without clogging or film.
Normal, combination, and oily/acne-prone skin that needs hydration without heaviness. Also ideal for redness-prone or easily sensitized skin that struggles with rich creams.
How to use
AM or PM after cleansing and serums. Apply a pea-sized amount to face and neck.
AM: finish with a broad-spectrum mineral SPF.
Pro pairing (simple, no moisturizer layering)
- Day: 4-Defy Gel Cream → Colorescience mineral SPF.
- Retinoid nights: retinoid → 4-Defy Gel Cream (to buffer without weight).
- Post-procedure (re-epithelialized): Epicutis Lipid Serum → 4-Defy Gel Cream for light comfort.
Ceramide NP, Phytosphingosine, Lactobacillus Ferment, Palmitoyl Tripeptide-38, Ergothioneine, Sodium Hyaluronate, Squalane, Caprylic/Capric Triglyceride.
Full INCI
Water (Aqua), Glycerin, Caprylic/Capric Triglyceride, Propanediol, Cetearyl Alcohol, Squalane, Cocos Nucifera (Coconut) Fruit Extract, Sodium Stearoyl Glutamate, Carbomer, Sodium Polyacrylate, Diisostearyl Malate, Hexylene Glycol, Sodium Phytate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Hydroxide, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Lactobacillus Ferment, Ceramide NP, Sodium Hyaluronate, Phytosphingosine, Palmitoyl Tripeptide-38, Ergothioneine.
Safety notes
Patch test first. Avoid use on broken/compromised skin. If highly sensitive, start once daily and increase as tolerated. Always use SPF in the morning.